Witryna1 wrz 2024 · Immune checkpoint inhibitors cause acute kidney injury (AKI), the most common being acute interstitial nephritis. •. In most cases, the acute interstitial nephritis is responsive to steroids. •. Chimeric antigen receptor T-cell therapy has a high rate of AKI, but with anti-interleukin-6 therapy, the rates are decreasing. •. Witryna1 wrz 2024 · Immunotherapies and renal injury. Goal of cancer immunotherapy is to engage the individual's own immune system to generate anti-tumor immunity. Immune checkpoint inhibitors and chimeric antigen T cell receptor therapy has revolutionized cancer care. Immunotherapies can cause acute kidney injury, glomerular diseases, …
Second-line tyrosine kinase inhibitor-therapy after …
WitrynaPurpose of review: Most contemporary metastatic renal-cell carcinoma patients receive first-line immunotherapy and tyrosine kinase inhibitor (TKI) combination or … Witryna7 kwi 2024 · A 58-year-old female presented with a right axillary mass, which was confirmed as Stage IB BRAF-mutant melanoma based on the histology of the resected mass.The patient’s history included a left upper arm melanoma that was resected in 2012; an allograft renal transplant secondary to polycystic kidney disease from a … high chair first birthday banner
Nephrotoxicity of recent anti-cancer agents Clinical Kidney …
Witryna3 kwi 2024 · In the case of AKI and chronic kidney disease (CKD), IL-6 increases fibroblast growth factor 23 levels, which may contribute to phosphaturia and … Witryna10 maj 2024 · On April 16, the Food and Drug Administration (FDA) approved the immunotherapy drugs nivolumab (Opdivo) and ipilimumab (Yervoy) in combination … WitrynaFinally, Dr. Choueiri discussed novel treatment approaches for patients with progression following immunotherapy. There are a number of ongoing and early-phase studies of at least twelve different treatment approaches, as highlighted below. One of the foremost targets among these novel approaches is targeting of HIF-2alpha: VHL deficiency ... highchair foldable